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Updated: Dec 26, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
Pediatric thyroid ultrasound: a radiologist's checklist
Ioanna Tritou1, Marina Vakaki2, Rodanthi Sfakiotaki2
1Department of Radiology, Venizeleion General Hospital of Heraklion, Crete, Greece.
Ultrasonography is key for pediatric thyroid evaluation, aiding diagnosis of congenital hypothyroidism and other conditions. A checklist helps interpret thyroid ultrasounds in children, considering their higher malignancy risk for nodules.
Area of Science:
- Pediatric Endocrinology
- Diagnostic Imaging
- Radiology
Background:
- Ultrasonography (US) is the primary imaging modality for pediatric thyroid evaluation.
- Congenital hypothyroidism, goiter, and autoimmune diseases are common pediatric thyroid conditions.
- Thyroid US is crucial for diagnosing various pediatric thyroid pathologies.
Purpose of the Study:
- To outline key sonographic findings in pediatric thyroid evaluations.
- To propose a standard checklist for performing and interpreting thyroid US in neonates and children.
- To emphasize differences in nodule evaluation between pediatric and adult populations.
Main Methods:
- Review of ultrasonographic findings in pediatric thyroid disease.
- Comparison of diagnostic considerations in newborns versus older children.
- Analysis of nodule characteristics and malignancy risk in pediatric thyroid cancer.
Main Results:
- Ultrasonography aids in diagnosing congenital hypothyroidism, goiter, and diffuse/solid thyroid diseases.
- Nodules in children have a higher malignancy likelihood, warranting a lower threshold for biopsy.
- Adult nodule classification systems are insufficient for pediatric thyroid nodules.
Conclusions:
- Ultrasonography is essential for pediatric thyroid assessment, complemented by other tests.
- A standardized approach and checklist are recommended for pediatric thyroid US.
- Early biopsy and lower size thresholds for nodules in children are crucial due to increased malignancy risk.
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