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Bracketed Radioactive Seed Localization for Breast Conservation Surgery.

Jordan Dixon1, Bharti Jasra2, Anita Ankola1

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The American Surgeon
|March 14, 2020
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Summary
This summary is machine-generated.

Bracketed seed localization using radioactive seeds for breast cancer can improve surgical margin outcomes. This technique may increase the number of patients eligible for breast-conserving surgery, reducing re-excision rates.

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Area of Science:

  • Oncology
  • Radiology
  • Surgical Oncology

Background:

  • Screening mammography detects breast cancers, often as calcifications.
  • Surgical margins and re-excision rates are critical in breast cancer treatment.
  • Seed localization is used for non-palpable breast lesions.

Purpose of the Study:

  • To evaluate surgical margin status and re-excision rates in patients with breast cancer.
  • To assess the efficacy of bracketed seed localization for biopsy-proven breast cancer.
  • To determine if bracketed seed localization impacts breast conservation rates.

Main Methods:

  • Retrospective review of 25 patients undergoing bracketed iodine-125 seed localization for breast cancer.
  • Patients had biopsy-proven ductal carcinoma in situ and/or invasive ductal carcinoma.
  • Surgical margins and re-excision rates were analyzed post-lumpectomy.

Main Results:

  • 32% (8/25) of patients required re-excision due to positive margins.
  • No significant difference in calcification size between re-excision and negative margin groups.
  • One patient was converted to mastectomy.

Conclusions:

  • Bracketed seed localization is a viable technique for delineating breast cancer calcifications.
  • This method may help achieve negative margins and facilitate breast conservation.
  • Further research can optimize seed placement for improved surgical outcomes.