Related Experiment Video

Updated: Dec 26, 2025

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

5.7K

Correlation Between the Severity of Coronary Artery Ectasia and Monocyte/Lymphocyte, Platelet/Lymphocyte, and HDL/LDL

Emre Ozdemir1, Ozgen Safak2, Mert Pehlivan AltIn1

  • 1Cardiology Clinic, Izmir Katip Çelebi University, Ataturk Education and Research Hospital, Izmir, Turkey.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|March 15, 2020
PubMed

Insights

The monocyte/lymphocyte and platelet/lymphocyte ratios correlate with coronary artery ectasia (CE) severity. These ratios can aid in evaluating follow-up and treatment success for CE patients.

Area of Science:

  • Cardiology
  • Biomarkers
  • Vascular Disease

Background:

  • Coronary artery ectasia (CE) is often overlooked compared to coronary stenosis.
  • Effective markers for assessing CE severity are needed for patient management.

Purpose of the Study:

  • To evaluate the efficacy of monocyte/lymphocyte, platelet/lymphocyte, and HDL/LDL ratios as indicators of coronary artery ectasia severity.

Main Methods:

  • A retrospective analysis of 7,923 coronary angiographs was conducted.
  • Inclusion criteria focused on significant coronary artery dilatation (>1.5 times).
  • Demographic data, CE type, clinical status, and specific blood ratios were collected.

Main Results:

  • 206 cases (2.6%) of CE were identified, with a mean age of 61.4 years.
  • A significant correlation was found between monocyte/lymphocyte ratio, platelet/lymphocyte ratio, and the degree of ectasia.
  • Hypertension, hyperlipidemia, and smoking were common comorbidities.

Conclusions:

  • The monocyte/lymphocyte ratio and platelet/lymphocyte ratio show consistency with CE severity.
  • These inflammatory markers may prove valuable in monitoring CE progression and treatment outcomes.
  • Increased clinical awareness and utilization of these ratios for CE evaluation are recommended.
Abstract

More Related Videos

Quantification of Monocyte Transmigration and Foam Cell Formation from Individuals with Chronic Inflammatory Conditions09:41

Quantification of Monocyte Transmigration and Foam Cell Formation from Individuals with Chronic Inflammatory Conditions

Published on: October 17, 2017

13.8K
Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

9.6K

Related Concept Videos

Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
300
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
792
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
537
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
684
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
308
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
152