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Presentations and Outcomes of Thyroid Storm
Muhammad Shahid1, Zareen Kiran1, Aqiba Sarfraz2
1National Institute of Diabetes & Endocrinology (NIDE), Dow University of Health Sciences (Ojha Campus) Karachi, Pakistan.
Summary
Thyroid storm patients in Karachi had a high mortality rate of 87.5%. Infections were the most frequent comorbidity, highlighting the critical nature of this endocrine emergency.
Area of Science:
- Endocrinology
- Internal Medicine
- Critical Care Medicine
Background:
- Thyroid storm is a life-threatening endocrine emergency.
- Limited data exists on thyroid storm characteristics and outcomes in Pakistan.
Purpose of the Study:
- To describe the clinical features and outcomes of thyroid storm patients.
- To identify factors associated with mortality in thyroid storm.
Main Methods:
- Retrospective review of thyroid storm patients (December 2018 - May 2019).
- Inclusion criteria: Age 18-70 years, fulfilling Burch-Wartofsky criteria.
- Data collected: Demographics, clinical presentation, comorbidities, laboratory findings.
Main Results:
- Eight patients were included; 62.5% were female, mean age 43 years.
- Infections were the most common comorbidity (62.5%), followed by cardiovascular (37.5%) and gastrointestinal (25%) diseases.
- In-hospital mortality rate was 87.5% (7 out of 8 patients).
Conclusions:
- Thyroid storm in Karachi is associated with extremely high mortality.
- Infections are a significant precipitating factor.
- Urgent and aggressive management is crucial for improving outcomes.
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