Vaccine skepticism reflects basic cognitive differences in mortality-related event frequency estimation
Related Experiment Video
Updated: Dec 26, 2025

Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses
Published on: September 28, 2018
1Texas Tech University, Psychological Sciences Building, 2700 18th St, Lubbock, TX 79410, United States.
Abstract:
Vaccines have prevented and nearly eliminated several deadly diseases, yet they face skepticism from the public. One potential driver of vaccine skepticism is how people process event frequencies such as rare adverse reactions to vaccines. Misestimations may distort the perceived risks of vaccinating. The current study examined how vaccine skepticism is related to accuracy in event frequency processing. In Experiment 1, participants (n = 158) estimated the frequencies of several vital statistics (e.g., 'How many people die per year in the U.S. from emphysema?'). Higher levels of vaccine skepticism were associated with lower accuracy in frequency estimation and over-estimation of rare events. In Experiment 2 (n = 109), we again found that vaccine skepticism was negatively associated with vital statistic estimation accuracy but not for emotionally neutral or positive events. These results suggest that vaccine skepticism may arise from basic individual differences in processing events associated with mortality or negative affect.
Related Concept Videos
The Availability Heuristic
Vaccinations
Bias in Epidemiological Studies
Causality in Epidemiology
Assumptions of Survival Analysis
Relative Risk

