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Principles of Disease Surveillance01:26

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
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Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
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Coronavirus disease 2019: What we know?

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Area of Science:

  • Infectious Diseases
  • Virology
  • Public Health

Background:

  • The emergence of novel infectious agents poses significant global health challenges.
  • A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified as the causative agent of a pneumonia outbreak in Wuhan, China, in late 2019.
  • The World Health Organization (WHO) named the disease coronavirus disease 2019 (COVID-19).

Purpose of the Study:

  • To provide a comprehensive review of the pathogen, clinical features, diagnosis, and treatment of COVID-19.
  • To briefly comment on the epidemiology and pathology of COVID-19 based on current evidence.
  • To consolidate existing knowledge on COVID-19 for researchers and clinicians.

Main Methods:

  • Literature review of scientific publications and reports.
  • Synthesis of information on the virology, clinical presentation, diagnostic methods, and therapeutic strategies for COVID-19.
  • Analysis of epidemiological data and pathological findings.

Main Results:

  • Detailed description of SARS-CoV-2, the virus responsible for COVID-19.
  • Overview of the clinical manifestations, ranging from mild to severe respiratory illness.
  • Summary of current diagnostic approaches and treatment options.

Conclusions:

  • COVID-19 represents a significant and rapidly evolving global health threat.
  • A thorough understanding of the pathogen, clinical aspects, and management is crucial for effective control.
  • Continued research into epidemiology, pathology, and treatment is essential.