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Structure-activity relationship of presenilin in γ-secretase-mediated intramembrane cleavage

Tetsuo Cai1, Taisuke Tomita1

  • 1Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, 113-0033, Japan.

Seminars in Cell & Developmental Biology
|March 16, 2020
PubMed

Keywords:
Alzheimer diseaseIntramembrane proteaseProteolysisStructureγ-Secretase

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