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Updated: Dec 26, 2025

Ole Isacson: Development of New Therapies for Parkinson's Disease
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Parkinson's disease treatment: past, present, and future

John D Elsworth1

  • 1Yale University School of Medicine, New Haven, CT, 06511, USA. john.elsworth@yale.edu.

Journal of Neural Transmission (Vienna, Austria : 1996)
|March 16, 2020
PubMed

Insights

Dr. Gerald Stern

Area of Science:

  • Neurology
  • Neuroscience
  • Genetics

Background:

  • Review of Dr. Gerald Stern's contributions to Parkinson's disease (PD) treatments.
  • Foundation for evaluating future PD management strategies.

Observation:

  • Current PD treatments focus on symptom control.
  • Future options require understanding environmental, genetic, and epigenetic factors.

Findings:

  • Emerging strategies include improving mitochondrial function and halting alpha-synuclein accumulation.
  • Refinement of stem cell and gene therapies shows promise.

Implications:

  • Advances depend on better disease models.
  • Future research aims to halt Parkinson's disease progression.
Keywords:
Gene therapyParkinson’s diseasePathologyPharmacologyReviewStem cells

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