Related Experiment Video
Updated: Dec 26, 2025

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
Published on: August 8, 2014
Ligneous gingivitis secondary to plasminogen deficiency: a multidisciplinary diagnostic challenge
Marshall MacPherson1, Mindy Pho2, Jacqueline Cox3
1Department of Dentistry, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Abstract:
Plasminogen deficiency is a genetic condition resulting in deposition of extravascular fibrin within mucosal tissues. Lesions associated with plasminogen deficiency most commonly affect the eyes, while intraoral lesions, when present, affect the marginal aspects of the gingiva. We report a diagnostically challenging case of ligneous gingivitis, which developed in a young male patient in the absence of other clinical lesions. Due to the rarity of this condition, it may fall under the radar of dentists and dental specialists, leading to missed or delayed diagnosis.
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Endocarditis II: Clinical Features of Infective Endocarditis
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

