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Related Experiment Video

Updated: Dec 26, 2025

Use of Electromagnetic Navigational Transthoracic Needle Aspiration E-TTNA for Sampling of Lung Nodules
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Needle deflection and tissue sampling length in needle biopsy.

Annie D R Li1, Jeffrey Plott2, Lei Chen3

  • 1Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.

Journal of the Mechanical Behavior of Biomedical Materials
|March 17, 2020
PubMed
Summary

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New multi-bevel needle tips can reduce deflection during biopsy, improving accuracy. This design change enhances tissue sampling length, crucial for precise cancer diagnosis and treatment.

Area of Science:

  • Biomedical Engineering
  • Surgical Instrumentation
  • Pathology

Background:

  • Needle biopsy is crucial for cancer diagnosis, but current single-bevel needles often deflect, leading to inaccurate sampling.
  • Understanding factors influencing needle deflection and tissue sampling length is vital for improving diagnostic accuracy.

Purpose of the Study:

  • To compare needle deflection and tissue sampling length between single-bevel and multi-bevel needle tip geometries.
  • To investigate the impact of tissue separation location on needle-tissue interaction and sampling outcomes.

Main Methods:

  • Coupled Eulerian-Lagrangian finite element analysis to model needle-tissue interaction.
  • Experimental validation using tissue-mimicking phantoms and ex-vivo tissue.
Keywords:
Needle biopsyNeedle deflectionNeedle insertionNeedle tip geometryTissue sampling

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Last Updated: Dec 26, 2025

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Main Results:

  • Needle tip geometry and tissue separation location significantly affect needle deflection and tissue sampling length.
  • Multi-bevel needle tips with specific separation points can reduce deflection while maintaining adequate sampling length.

Conclusions:

  • Optimizing needle tip geometry, particularly with multi-bevel designs, can minimize deflection during biopsy.
  • Improved needle design can enhance precision in tissue sampling, leading to more accurate cancer diagnosis and treatment planning.