Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Neurofilament light chain as a tool for assessing disease activity and treatment response in Multiple Sclerosis].

Fortschritte der Neurologie-Psychiatrie·2026
Same author

From measurement to biomarker trajectories: platform-agnostic Z score analysis of serum NfL and GFAP in ocrelizumab-treated multiple sclerosis.

Journal of neurology·2026
Same author

Are Traditional Registries Becoming Obsolete in the Modern Digital Health Ecosystem?

Journal of medical Internet research·2026
Same author

Exploring attitudes and acceptance of artificial intelligence in multiple sclerosis from the patient perspective.

PLOS digital health·2026
Same author

Brain age gap in multiple sclerosis: associated with disability but independent of serum biomarkers.

Therapeutic advances in neurological disorders·2026
Same author

[Digital transformation in multiple sclerosis: Advances in diagnostics, monitoring and patient-centred care].

Fortschritte der Neurologie-Psychiatrie·2026

Related Experiment Video

Updated: Dec 26, 2025

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients
09:17

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients

Published on: May 17, 2020

3.7K

Balance Testing in Multiple Sclerosis-Improving Neurological Assessment With Static Posturography?

Hernan Inojosa1, Dirk Schriefer1, Antonia Klöditz1

  • 1MS Center, Center of Clinical Neuroscience, Department of Neurology, Carl Gustav Carus University Hospital, University of Dresden, Dresden, Germany.

Frontiers in Neurology
|March 17, 2020
PubMed
Summary

Static posturography offers an objective measure of balance for people with Multiple Sclerosis (pwMS), detecting issues even when clinical tests appear normal. This quantitative method enhances early diagnosis and preventive care for MS-related balance problems.

Keywords:
Romberg testbalanceexpanded disability status scalemultiple sclerosissensitivitystatic posturography

More Related Videos

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

11.9K
Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications
06:28

Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications

Published on: September 1, 2023

5.9K

Related Experiment Videos

Last Updated: Dec 26, 2025

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients
09:17

Quantitative Static and Dynamic Assessment of Balance Control in Stroke Patients

Published on: May 17, 2020

3.7K
Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

11.9K
Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications
06:28

Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications

Published on: September 1, 2023

5.9K

Area of Science:

  • Neurology
  • Biomedical Engineering
  • Rehabilitation Medicine

Background:

  • Balance problems significantly impact the quality of life for people with Multiple Sclerosis (pwMS), even in early disease stages.
  • Current assessments like the Expanded Disability Status Scale (EDSS) rely on subjective neurological examination, including the Romberg test for balance.
  • Objective quantification of postural stability is needed for early detection and preventive care in pwMS.

Purpose of the Study:

  • To evaluate static posturography as an objective tool to supplement the EDSS examination in assessing balance in pwMS.
  • To determine if static posturography provides additional information regarding cerebellar function and balance in early-stage Multiple Sclerosis.
  • To compare the postural stability of pwMS with healthy subjects using static posturography.

Main Methods:

  • A cross-sectional study involving 99 pwMS and 30 healthy subjects.
  • Static posturography using a force platform to measure delineated area, average speed, and average sway.
  • Statistical analysis included unpaired t-tests, ANOVA with post-hoc comparisons, and Spearman correlations with EDSS-associated outcomes.

Main Results:

  • PwMS demonstrated significantly worse performance in all three balance parameters compared to healthy controls (p < 0.001).
  • Static posturography identified significant balance deficits in pwMS even when their EDSS Romberg test score was normal.
  • Significant correlations were found between posturography measures (delineated area, average speed) and EDSS, cerebellar function score, and Romberg test results (r's from 0.330 to 0.537, p < 0.001).

Conclusions:

  • Static posturography serves as an objective and quantitative complement to the subjective EDSS neurological assessment.
  • This technique is particularly valuable for detecting subtle balance impairments in early-stage Multiple Sclerosis.
  • Objective balance assessment can aid in earlier diagnosis and more targeted preventive medical care for pwMS.