Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Routh-Hurwitz Criterion II01:19

Routh-Hurwitz Criterion II

818
In the application of the Routh-Hurwitz criterion, two specific scenarios can arise that complicate stability analysis.
The first scenario occurs when a singular zero appears in the first column of the Routh table. This situation creates a division by zero issues. To resolve this, a small positive or negative number, denoted as epsilon (∈), is substituted for the zero. The stability analysis proceeds by assuming a sign for ∈. If ∈ is positive, any sign change in the first...
818
Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

4.5K
The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an...
4.5K
Survival Tree01:19

Survival Tree

335
Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
 Building a Survival Tree
Constructing a...
335
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

1.0K
This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
1.0K
Routh-Hurwitz Criterion I01:15

Routh-Hurwitz Criterion I

473
Consider an electrical power grid, where stability is essential to prevent blackouts. The Routh-Hurwitz criterion is a valuable tool for assessing system stability under varying load conditions or faults. By analyzing the closed-loop transfer function, the Routh-Hurwitz criterion helps determine whether the system remains stable.
To apply the Routh-Hurwitz criterion, a Routh table is constructed. The table's rows are labeled with powers of the complex frequency variable s, starting from the...
473
Sampling Plans01:23

Sampling Plans

819
Sampling is a crucial step in analytical chemistry, allowing researchers to collect representative data from a large population. Common sampling methods include random, judgmental, systematic, stratified, and cluster sampling.
Random sampling is a method where each member of the population has an equal chance of being selected for the sample. It involves selecting individuals randomly, often using random number generators or lottery-type methods. For example, when analyzing the properties of a...
819

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Where do we go from here? Current state of drug-target binding kinetics and a roadmap to their establishment in drug discovery campaigns.

Drug discovery today·2026
Same author

Mesoglea biogenesis reveals a cryptic aboral valve for pressure regulation in cnidarian morphogenesis.

Science advances·2026
Same author

A correlative workflow for synaptic imaging by cryo-electron tomography.

Structure (London, England : 1993)·2026
Same author

MedicoSAM: Robust Improvement of SAM for Medical Imaging.

IEEE transactions on medical imaging·2025
Same author

H&E-based MSI/MMR testing with AI in colorectal cancer: a multi-centred blinded evaluation.

NPJ digital medicine·2025
Same author

Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing.

Science advances·2025

Related Experiment Video

Updated: Dec 26, 2025

Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm
11:53

Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm

Published on: December 9, 2012

13.3K

The Mutex Watershed and its Objective: Efficient, Parameter-Free Graph Partitioning.

Steffen Wolf, Alberto Bailoni, Constantin Pape

    IEEE Transactions on Pattern Analysis and Machine Intelligence
    |March 17, 2020
    PubMed
    Summary

    We introduce the Mutex Watershed, an efficient graph partitioning algorithm for image segmentation. This method identifies image segments without seeds or thresholds, achieving state-of-the-art results on benchmarks.

    More Related Videos

    Watershed Planning within a Quantitative Scenario Analysis Framework
    12:44

    Watershed Planning within a Quantitative Scenario Analysis Framework

    Published on: July 24, 2016

    8.4K
    Parameterizing V-notch Weir Equations for Flow Monitoring in a Drainage Control Structure
    07:15

    Parameterizing V-notch Weir Equations for Flow Monitoring in a Drainage Control Structure

    Published on: April 25, 2025

    879

    Related Experiment Videos

    Last Updated: Dec 26, 2025

    Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm
    11:53

    Spatial Multiobjective Optimization of Agricultural Conservation Practices using a SWAT Model and an Evolutionary Algorithm

    Published on: December 9, 2012

    13.3K
    Watershed Planning within a Quantitative Scenario Analysis Framework
    12:44

    Watershed Planning within a Quantitative Scenario Analysis Framework

    Published on: July 24, 2016

    8.4K
    Parameterizing V-notch Weir Equations for Flow Monitoring in a Drainage Control Structure
    07:15

    Parameterizing V-notch Weir Equations for Flow Monitoring in a Drainage Control Structure

    Published on: April 25, 2025

    879

    Area of Science:

    • Computer Vision
    • Image Processing
    • Graph Theory

    Background:

    • Image segmentation decomposes images into meaningful regions or closed contours.
    • Prior methods often rely on seeds, thresholds, or computationally intensive NP-hard formulations like multicut clustering.
    • A need exists for efficient, seedless, and threshold-free image segmentation algorithms.

    Purpose of the Study:

    • To propose an efficient and novel algorithm for image partitioning (segmentation without semantics).
    • To develop a method that accommodates both attractive and repulsive cues for flexible segmentation.
    • To demonstrate the algorithm's global optimality and competitive performance on benchmark datasets.

    Main Methods:

    • The study introduces the "Mutex Watershed," an efficient graph partitioning algorithm.
    • This algorithm utilizes attractive and repulsive cues, eliminating the need for explicit seeds or tunable thresholds.
    • The method's global optimality is proven in relation to multicut/correlation clustering formulations.

    Main Results:

    • The Mutex Watershed algorithm is deterministic, simple to implement, and exhibits empirical linearithmic complexity.
    • It successfully segments images into an unspecified number of regions using attractive and repulsive cues.
    • When combined with deep neural network cues, it achieved top performance on the ISBI 2012 EM segmentation benchmark.

    Conclusions:

    • The Mutex Watershed offers an efficient and effective solution for image segmentation without semantics.
    • The algorithm's ability to handle diverse cues and its proven optimality make it a significant advancement.
    • It represents the current state-of-the-art for specific image segmentation tasks, particularly in electron microscopy data.