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A Novel In Vitro Model of Blast Traumatic Brain Injury
Published on: December 21, 2018
Pelvic injury patterns in blast: Morbidity and mortality
Iain A Rankin1, Claire E Webster, Iain Gibb
1From the The Royal British Legion Centre for Blast Injury Studies, Department of Bioengineering (I.A.R., C.E.W., I.G., J.C.C., S.D.M.), Imperial College London, London; and Centre for Defence Radiology (I.G.), HMS Nelson, Portsmouth, United Kingdom.
Blast-related pelvic fractures in military casualties have a high mortality rate, primarily due to vascular injury. Early management should focus on controlling pelvic bleeding to reduce fatalities.
Area of Science:
- Trauma surgery
- Military medicine
- Injury epidemiology
Background:
- Blast trauma poses severe risks, with pelvic injuries being particularly critical.
- The incidence, mortality, and risk factors for blast-related pelvic trauma remain largely unquantified.
- Existing data lack assessment of clinical or radiological indicators for mortality in these cases.
Purpose of the Study:
- To determine the incidence and mortality of blast-mediated pelvic fractures.
- To identify clinical and radiological predictors of mortality in casualties with pelvic trauma.
- To assess the relative risk of specific injuries associated with blast-related pelvic fractures.
Main Methods:
- Analysis of the UK Joint Theater Trauma Registry (2003-2014).
- Inclusion of casualties with blast-mediated pelvic fractures from conflicts in Iraq and Afghanistan.
- Exclusion of casualties with severe injuries remote to the pelvis; computed tomography image analysis performed.
Main Results:
- 159 casualties identified with a 36% overall mortality rate.
- Pelvic vascular injury was present in all fatalities and had the highest relative risk of death (56% mortality).
- Unstable pelvic fractures, traumatic amputation, and perineal injuries were associated with a threefold increased risk of pelvic vascular injury.
Conclusions:
- Dismounted blast casualties with pelvic fractures face significant risk of noncompressible pelvic vascular injury.
- Initial management must prioritize control of noncompressible pelvic bleeding.
- Mitigation strategies targeting lateral pelvic displacement could reduce fatalities and injury burden.
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