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Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation

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Dig & Delve into Protein Based Nanoformulations.

Mohammad Shariq¹, Saba Parveen¹, Arshiya Shamim¹

¹Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, India.

|March 17, 2020

Summary

Protein nanoformulations offer a promising future for drug delivery and theranostics. These advanced formulations utilize various proteins as carriers for therapeutics, enhancing drug targeting and efficacy.

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Area of Science:

Nanotechnology
Pharmaceutical Science
Biomaterials

Background:

Nanotechnology has revolutionized pharmaceutical science, with nanoformulations showing significant potential in therapeutics and theranostics.
Protein-based nanoformulations are gaining attention due to their dual role as therapeutics and carriers.
These nanoformulations can encapsulate diverse agents like drugs, dyes, and contrast agents, broadening their applications.

Purpose of the Study:

To review various protein-based nanoformulations.
To highlight the potential of protein nanoformulations in drug delivery.
To discuss specific protein examples used in nanoformulations.

Main Methods:

Literature review of protein-based nanoformulations.
Discussion of different protein sources including human serum albumin, bovine serum albumin, soy protein isolate, phycocyanin, casein, bromelain, collagen, and sericin.
Analysis of the advantages of nano-sized protein formulations.

Main Results:

Protein nanoformulations demonstrate versatility in carrying various therapeutic agents.
Nanoformulation overcomes limitations associated with native proteins.
Specific proteins like albumin, casein, and collagen show promise as carriers and therapeutics.

Conclusions:

Protein-based nanoformulations represent a significant advancement in drug delivery.
These formulations offer enhanced therapeutic potential and overcome native protein limitations.
Further research into protein nanoformulations is crucial for future drug delivery systems.