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Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

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Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
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Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
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Response: Impact of anesthetic drugs on venous filtration of intravascular gas.

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Chronic decompression illness cognitive dysfunction improved with hyperbaric oxygen: a case report.

Kimberly T Bradley1, Jamie L Jamie L Krassow2, Michael F Richards1

  • 159th Medical Wing, Undersea and Hyperbaric Medicine, Joint Base San Antonio - Lackland, Texas U.S.

Undersea & Hyperbaric Medicine : Journal of the Undersea and Hyperbaric Medical Society, Inc
|March 17, 2020
PubMed
Summary
This summary is machine-generated.

Hyperbaric oxygen therapy (HBO2) helped an aircrew member recover from decompression illness symptoms after altitude chamber training. Serial cognitive tests showed significant improvement after 58 HBO2 treatments.

Keywords:
ANAMair embolismaltitudecase reportscognitivedecompression illnesshyperbaric oxygen therapy

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Area of Science:

  • Aerospace Medicine
  • Neurology
  • Hyperbaric Medicine

Background:

  • Altitude chamber training simulates high-altitude conditions, posing risks of hypoxia and decompression illness (DCI).
  • DCI can occur after training or during flight above 18,000 feet, requiring emergent treatment.
  • Hyperbaric oxygen (HBO2) therapy is the definitive treatment for DCI, reducing bubble size and improving tissue oxygenation.

Observation:

  • A 27-year-old female aircrew member experienced neurological symptoms including paresthesia, cognitive decline, and speech difficulties after altitude chamber training.
  • Her symptoms mimicked those of chronic traumatic brain injury (TBI).
  • Pre-deployment cognitive assessments (ANAM) were available for baseline comparison.

Findings:

  • The patient underwent 58 hyperbaric oxygen treatments over 14 months.
  • Serial cognitive testing demonstrated a near-return to her pre-deployment baseline scores.
  • The use of baseline ANAM tests allowed for objective monitoring of treatment efficacy.

Implications:

  • This case highlights the potential of HBO2 therapy for managing chronic neurological deficits resulting from DCI.
  • Objective cognitive monitoring is crucial for assessing treatment response in such cases.
  • Findings suggest HBO2 may be a viable therapeutic option for aircrew experiencing persistent neurological symptoms post-altitude exposure.