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Transradial and Transfemoral Approach in Patients with Prior Coronary Artery Bypass Grafting
Rafał Januszek1,2, Zbigniew Siudak3, Krzysztof Piotr Malinowski4
1University of Physical Education, Department of Clinical Rehabilitation, 31-571 Kraków, Poland.
Insights
For patients undergoing percutaneous coronary interventions (PCIs) after coronary artery bypass grafting (CABG), femoral access is linked to higher risks of periprocedural death and cardiac arrest compared to radial access.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Access
Background:
- Percutaneous coronary interventions (PCIs) are common treatments for coronary artery disease.
- Patients with prior coronary artery bypass grafting (CABG) represent a complex subgroup undergoing PCI.
- The choice of vascular access site for PCI in CABG patients requires careful consideration due to potential complications.
Purpose of the Study:
- To investigate the association between vascular access type and periprocedural complications in patients with a history of CABG undergoing PCI.
- To compare complication rates between femoral and radial access, as well as right and left radial access in this specific patient population.
Main Methods:
- Analysis of a Polish nationwide registry (ORPKI) of 536,826 PCIs from 2014-2018.
- Extraction of 32,225 patients with a prior history of CABG.
- Propensity score matching (PSM) followed by multifactorial analysis to compare femoral vs. radial and right vs. left radial access.
Main Results:
- Femoral access was significantly associated with higher rates of periprocedural death (OR: 1.79) and cardiac arrest (OR: 1.98) compared to radial access.
- After adjusting for Killip class and pre-PCI cardiac arrest, femoral access remained linked to increased procedural cardiac arrests (OR: 1.55).
- No significant differences in complications were observed between right and left radial access.
Conclusions:
- Femoral access in CABG patients undergoing PCI is associated with a higher risk of periprocedural cardiac arrests compared to radial access.
- Radial access appears to be a safer option for PCI in patients with prior CABG history.
- Further research may be warranted to explore specific strategies to mitigate risks associated with femoral access in this cohort.
Abstract:
The relationship between periprocedural complications and the type of vascular access in patients with prior history of coronary artery bypass grafting (CABG) and treated with percutaneous coronary interventions (PCIs) is less investigated than in the overall group of patients treated with PCI. The aim of the current study was to assess the relationship between the type of vascular access and selected periprocedural complications in a group of patients with prior history of CABG and treated with PCIs. Based on a Polish nationwide registry of interventional cardiology procedures called ORPKI, the authors analyzed 536,826 patients treated with PCI between 2014 and 2018. The authors extracted 32,225 cases with prior history of CABG. Then, patients with femoral and radial access as well as right and left radial access were compared. This comparison was proceeded by propensity score matching (PSM). After PSM, a multifactorial analysis revealed that patients treated with PCI from femoral access were significantly more often related to periprocedural deaths (odds ratio [OR]: 1.79; 95%, confidence interval [CI]: 1.1-3.0, p = 0.02) and cardiac arrests (OR: 1.98; 95%, CI: 1.38-2.87, p < 0.001). After inclusion of the Killip class grade and the occurrence of cardiac arrests before PCI into the PSM, the significance remained for procedural related cardiac arrests (OR: 1.55; 95%, CI: 1.07-2.28, p = 0.022]). However, a comparison of right and left radial access showed no significant differences between procedure-related complications. It has been confirmed that there is a statistical association between femoral access (compared to radial access) and a higher rate of periprocedural cardiac arrests in patients with prior history of CABG treated with PCI.
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