Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electroacoustic single-cell spectroscopy for morphological differentiation of red blood cells: An in silico feasibility study.

JASA express letters·2026
Same author

Temporal Changes in Continuous Glucose Monitoring Profiles in Health Care Workers Participating in a Digitally Delivered Metabolic Wellness Program.

Journal of diabetes science and technology·2026
Same author

Ambient black carbon and its dependence on in situ stubble burning.

Environmental monitoring and assessment·2026
Same author

Brighter nights, greater health risks: intensity-dependent disruptions by nighttime light exposure on sleep and metabolism in diurnal zebra finches.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2026
Same author

Predicting Craving-Related Emotions among Opioid Use Disorder Patients: Preliminary Results.

... International Conference on Wearable and Implantable Body Sensor Networks. International Conference on Wearable and Implantable Body Sensor Networks·2026
Same author

Accurate and fast event-based shape measurement of mixed reflectance scenes.

Nature communications·2026

Related Experiment Video

Updated: Dec 26, 2025

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation
07:20

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation

Published on: August 30, 2017

8.8K

PulseCam: a camera-based, motion-robust and highly sensitive blood perfusion imaging modality.

Mayank Kumar1, James W Suliburk2, Ashok Veeraraghavan1

  • 1Electrical and Computer Engineering, Rice University, 6100 Main St, Houston, TX, 77005, USA.

Scientific Reports
|March 18, 2020
PubMed
Summary

PulseCam is a new camera-based system that accurately measures blood perfusion, even with patient movement. It combines camera video with pulse oximeter data for reliable imaging.

More Related Videos

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
11:35

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

Published on: December 8, 2010

16.9K
Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
09:56

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

11.2K

Related Experiment Videos

Last Updated: Dec 26, 2025

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation
07:20

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation

Published on: August 30, 2017

8.8K
Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
11:35

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

Published on: December 8, 2010

16.9K
Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
09:56

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

11.2K

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Physiology

Background:

  • Blood perfusion is critical for cell viability, and its measurement has significant clinical applications.
  • Existing camera-only methods for blood perfusion imaging face challenges with motion artifacts and signal recovery.
  • Accurate blood perfusion monitoring is essential for diagnosing and managing various medical conditions.

Purpose of the Study:

  • To develop PulseCam, a novel camera-based imaging modality for robust and sensitive blood perfusion measurement.
  • To overcome limitations of existing methods, specifically motion artifacts and signal-to-noise ratio issues.
  • To provide a cost-effective and user-friendly device for blood perfusion visualization and analysis.

Main Methods:

  • Developed PulseCam, integrating camera video with conventional pulse oximeter data.
  • Employed a novel brightness-invariant optical flow algorithm for robust video stabilization.
  • Validated the system's performance through a pilot clinical study in a surgical setting.

Main Results:

  • PulseCam achieves 1 mm spatial and 1 frame-per-second temporal resolution.
  • Reduced blood perfusion estimation error to below 10% in motion scenarios, outperforming current approaches.
  • Demonstrated superior sensitivity and response time compared to infrared thermography.
  • Successfully detected subtle blood flow changes and occlusions, including venous occlusion.
  • Confirmed robustness and reliability in challenging operating room environments.

Conclusions:

  • PulseCam offers a motion-robust, highly sensitive, and cost-effective solution for blood perfusion imaging.
  • The system overcomes key limitations of existing camera-only modalities.
  • PulseCam shows promise as a bedside and point-of-care device for easy-to-use blood perfusion analysis.