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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

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CT protocol optimisation in PET/CT: a systematic review.

V Bertolini¹, A Palmieri², M C Bassi³

¹Medical Physics Unit, Azienda USL-IRCCS, Reggio Emilia, Italy.

|March 18, 2020

Summary

This summary is machine-generated.

This review highlights variability in CT protocols for PET/CT scans. Optimizing CT protocols is crucial for dose reduction in PET/CT examinations, especially with new technologies.

Keywords:

CT protocol optimisation Computed tomography PET/CT

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Area of Science:

Medical Imaging
Radiology
Nuclear Medicine

Background:

Current guidelines for CT scans in PET/CT are inconsistent.
This review examines CT protocols used in PET/CT examinations.

Purpose of the Study:

To provide an overview of CT protocols in PET/CT.
To determine the purposes of CT scans within PET/CT.
To assess if CT protocols are derived from dose optimization studies.

Main Methods:

Systematic literature search (PubMed/MEDLINE, Cochrane Library, Embase, Scopus) from Jan 2007 to June 2019.
Analysis of 87 CT protocols across adult, child, and phantom subgroups.
Categorization of CT intents (anatomic localization, attenuation correction, diagnostic) and calculation of CTDIvol for dose comparison.

Main Results:

Significant variation found in CT acquisition parameters, notably tube current-time product.
Dose optimization (CTDIvol) showed a statistically significant dependence on protocol intent (p = 0.002).
Diagnostic protocols with contrast had higher CTDIvol than those without (p = 0.009).

Conclusions:

Effective dose optimization in PET/CT relies on appropriate CT protocol implementation.
Periodic quality control audits are recommended to align with technological advancements and standardize protocols.
There is a need to better define CT protocol usage in PET/CT, considering evolving technologies.