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Updated: Dec 26, 2025
Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
Published on: September 4, 2017
Giant intraventricular and paraventricular cavernous malformations with multifocal subependymal cavernous
Suwadee Eng-Chuan1, Supika Kritsaneepaiboon2, Anukoon Kaewborisutsakul3
1Department of Radiology, Faculty of Medicine, Prince of Songkla University, Hat Yai 90110, Thailand.
Insights
Giant cavernous malformations (GCMs) in the ventricles are rare in children. Characteristic MRI findings aid in diagnosing these rare intraventricular tumors.
Area of Science:
- Neuroimaging
- Pediatric Neurology
- Neurosurgery
Background:
- Giant cavernous malformations (GCMs) are uncommon, particularly in intraventricular and paraventricular locations within the brain.
- This study focuses on the rare occurrence of GCMs in these specific pediatric brain regions.
Observation:
- Presents two pediatric cases of intraventricular and paraventricular GCMs in infants (6 and 21 months old).
- Includes a comprehensive literature review examining GCMs based on their location and associated imaging characteristics.
Findings:
- Magnetic resonance imaging (MRI) reveals characteristic features of GCMs, including multicystic lesions.
- Distinctive MRI findings like a hemosiderin ring or "bubbles-of-blood" appearance are crucial for diagnosis.
- These imaging findings assist in differentiating GCMs from other hemorrhagic intraventricular masses.
Implications:
- Multifocal intraventricular and/or paraventricular GCMs represent a rare entity in young children.
- Characteristic MRI findings are essential for distinguishing GCMs from other intraventricular tumors in pediatric patients.
- Accurate diagnosis through advanced imaging facilitates appropriate clinical management and treatment strategies.
Background:
Giant cavernous malformation (GCM) is rarely found in intraventricular or paraventricular locations.
Case Summary:
We present two cases of 6-mo and 21-mo boys with intraventricular and paraventricular GCMs including a literature review focused on location and imaging findings. Characteristic magnetic resonance imaging findings such as multicystic lesions and a hemosiderin ring or bubbles-of-blood appearance can assist in the differential diagnosis of a hemorrhagic intraventricular and/or paraventricular mass.
Conclusion:
Multifocal intraventricular and/or paraventricular GCM in small children is rare. The characteristic magnetic resonance imaging findings can help to differentiate GCMs from other intraventricular tumors.
