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Elastic fiber contains the protein elastin along with lesser amounts of other proteins and glycoproteins. The main property of elastin is that it will return to its original shape after being stretched or compressed. Elastic fibers are prominent in elastic tissues found in skin and the elastic ligaments of the vertebral column.
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Dense connective tissue contains more collagen fibers than loose connective tissue. As a consequence, it displays greater resistance to stretching. There are two major categories of dense connective tissue— regular and irregular.
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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Fascia, a thin layer of fibrous connective tissue, is distributed throughout the body. It demarcates and forms a supportive covering over skeletal muscles, bones, blood vessels, and organs. There are three main types of facia— superficial fascia, deep fascia, and subserous fascia. These are all present at different depths in the body. Fascia reduces the friction and permits muscles, joints, and organs to easily slide against each other, facilitating movement of the body and preventing...
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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Three main types of fibers are secreted by fibroblasts: collagen fibers, elastic fibers, and reticular fibers. Collagen fiber is made from fibrous protein subunits linked together to form a long, straight fiber. Collagen fibers, while flexible, have great tensile strength, resist stretching, and give ligaments and tendons their characteristic resilience and strength. These fibers hold connective tissues together, even during the body's movement.
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Elastofibroma Dorsi: A Rare Connective Tissue Tumor.

Mohamed S Suliman1, Zachary S Higginbothom1, Ahmed Amro2

  • 1Internal Medicine, Marshall University, Joan C. Edwards School of Medicine, Huntington, USA.

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|March 18, 2020
PubMed
Summary

Elastofibroma dorsi (ED) is a benign tumor often found near the scapula. Biopsy is usually unnecessary, and treatment is only recommended for symptomatic cases to avoid misdiagnosis.

Keywords:
benign tumorelastofibromasoft tissue mass

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Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Elastofibroma dorsi (ED) is a rare, benign connective tissue tumor.
  • It typically presents as a slow-growing mass, often on the inferior scapula.
  • ED can be mistaken for malignancy, causing patient anxiety.

Observation:

  • A 70-year-old female, post-lung cancer resection, presented with a scapular lump.
  • Multiple specialists evaluated the patient, and a biopsy confirmed Elastofibroma dorsi.
  • The patient's apprehension stemmed from the possibility of malignancy.

Findings:

  • Biopsy confirmed the scapular mass as Elastofibroma dorsi.
  • This benign soft tissue tumor does not require aggressive diagnostic workup.
  • Treatment is reserved for symptomatic presentations.

Implications:

  • Educating physicians about ED is crucial to prevent unnecessary diagnostic procedures.
  • Timely diagnosis of ED can reduce patient anxiety and healthcare costs.
  • Asymptomatic ED lesions warrant observation rather than surgical intervention.