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Primary Central Nervous System Lymphoma Involving Entire Ventricular System
Hemant Kumar1, Achal Sharma1, Vinod Sharma1
1Department of Neurosurgery, S.M.S. Medical College, Jaipur, Rajasthan, India.
Asian Journal of Neurosurgery
|March 18, 2020
Summary
Primary central nervous system lymphoma (PCNSL) is a rare brain tumor. This case highlights a unique presentation of PCNSL involving the entire ventricular system in an immunocompetent patient.
Area of Science:
- Neuro-oncology
- Hematology
- Pathology
Background:
- Primary central nervous system lymphoma (PCNSL) comprises a small fraction (<1%-4%) of primary central nervous system tumors.
- PCNSLs are predominantly diffuse large B-cell lymphomas (90%), with a minority being T-cell lymphomas (10%).
Observation:
- A rare case of PCNSL is presented in a 36-year-old immunocompetent male.
- The patient exhibited symptoms including severe headache, decreased vision, and unsteady gait.
- The tumor manifested as an intracranial mass extensively involving the entire ventricular system.
Findings:
- Histopathological examination and subsequent immunohistochemistry confirmed the diagnosis of PCNSL.
- The findings underscore the diverse clinical presentations of PCNSL.
Implications:
- This case expands the understanding of rare PCNSL presentations.
- Early diagnosis through histopathology is crucial for effective management of CNS lymphomas.
- Highlights the importance of considering PCNSL in immunocompetent individuals with atypical neurological symptoms.
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