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Using the revised Edmonton symptom assessment scale during neoadjuvant radiotherapy for retroperitoneal sarcoma
Russell F Palm1, Heather S L Jim2, David Boulware3
1Department of Radiation Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Clinical and Translational Radiation Oncology
|March 18, 2020
Summary
Weekly symptom reporting using the Revised Edmonton Symptom Assessment Scale (ESAS-r-CSS) during pre-operative radiotherapy for retroperitoneal sarcoma (RPS) helped manage patient anxiety and pain. This proactive approach can minimize symptom progression and treatment interruptions.
Area of Science:
- Oncology
- Symptom Management
- Radiotherapy
Background:
- Retroperitoneal sarcoma (RPS) is a rare cancer requiring multidisciplinary care.
- The Revised Edmonton Symptom Assessment Scale (ESAS-r-CSS) aids proactive symptom management.
- This study evaluates ESAS-r-CSS screening during pre-operative radiotherapy for RPS patients.
Purpose of the Study:
- To report the results of ESAS-r-CSS screening during pre-operative radiotherapy for RPS patients.
- To assess symptom changes during neoadjuvant radiotherapy for RPS.
- To identify factors associated with symptom severity.
Main Methods:
- Reviewed records of 47 RPS patients (2015-2018).
- Analyzed weekly ESAS-r-CSS data from 29 non-metastatic patients receiving neoadjuvant radiotherapy.
- Used generalized estimating equation model to compare 13 symptoms to baseline and assess covariate effects.
Main Results:
- Anxiety scores decreased significantly by week 3 (P=0.01).
- Pain scores decreased significantly by week 5 (P=0.01).
- Constipation worsened by week 2 (P=0.02). Female gender, older age, higher dose, and larger tumor size correlated with worse symptoms.
Conclusions:
- Weekly ESAS-r-CSS reporting facilitates timely symptom management in RPS patients undergoing radiotherapy.
- Proactive symptom monitoring can minimize side effects and treatment interruptions.
- This approach is valuable for managing the unique challenges of RPS.
