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Updated: Dec 26, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Malignant melanoma in a child with giant congenital melanocytic nevus and satellite flekers: A rare entity
Manju Kumari1, Mukul Singh1, Pallavi Punhani1
1Department of Pathology, V.M.M.C and Safdarjung Hospital, New Delhi, India.
Abstract:
Malignant melanomas in the pediatric age are remarkably rare representing 0.9% of various pediatric malignancies. Congenital nevi occur in 1 in 100 newborns, whereas giant congenital melanocytic nevus (GCMN) measuring more than 20 cm is seen in 1 in 20 000 cases. Very few cases of malignant melanoma arising from GCMN have been described in English literature. The risk of developing malignant melanoma from GCMN is believed to be directly proportional to the size of the nevus and varies from 2.6% to 20% depending on the size of nevus. We present a case of malignant melanoma in a 12-year-old female child who had a congenital giant nevus and multiple satellite flekers all over the body.
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