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The Multiple Sclerosis Health Resource Utilization Survey (MS-HRS): Development and Validation Study.

Nils-Henning Ness1, Rocco Haase1, Raimar Kern2

  • 1University Hospital Carl Gustav Carus, Dresden, Germany.

Journal of Medical Internet Research
|March 18, 2020
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Summary

A new survey, the Multiple Sclerosis Health Resource Utilization Survey (MS-HRS), has been developed and validated. This tool allows for reliable assessment of healthcare costs in multiple sclerosis (MS) patients.

Keywords:
multiple sclerosispatient-reported outcome measuresquestionnaire developmentresource utilizationvalidation

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Area of Science:

  • Health Economics
  • Clinical Research
  • Patient-Reported Outcomes

Background:

  • Economic impact studies in multiple sclerosis (MS) often rely on surveys.
  • Existing surveys lack validation, hindering comparisons and conclusions on long-term treatment efficiency.

Purpose of the Study:

  • To develop and validate a tablet- and paper-based health resource utilization survey for MS patients.
  • To establish a reliable and valid tool for assessing healthcare resource use in MS.

Main Methods:

  • Developed the Multiple Sclerosis Health Resource Utilization Survey (MS-HRS) with 24 cost items.
  • Validated the survey using data from two large German observational studies.
  • Assessed practicability via response rate (92.4%), reliability (test-retest ICC=0.828), and construct validity (convergent and discriminant).

Main Results:

  • The MS-HRS demonstrated good practicability and reliability.
  • Convergent validity showed positive correlation between total costs and disability (r=0.411).
  • Mean annual cost was €28,203 (US $39,203) with disease-modifying therapies.

Conclusions:

  • The MS-HRS is a multilingual, reliable, and valid questionnaire.
  • It offers a holistic assessment of resource utilization in MS patients.
  • The survey is electronically available and easy to administer for cross-sectional and longitudinal studies.