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Updated: Dec 26, 2025

Isolation of Sertoli Cells and Peritubular Cells from Rat Testes
Published on: February 8, 2016
Disorders of Puberty: Endocrinology of the Pre-Pubertal Testis
Sandro La Vignera1, Rossella Cannarella1, Rosita A Condorelli1
1Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Abstract:
Male infertility is a widespread condition among western countries. Meta-regression data show that sperm concentration and total sperm count have halved in the last decades. The reasons of this decline are still unclear. The evaluation of testicular function in pre-pubertal children may be effective in the timely detection of Sertoli cell (SC) disfunction, which anticipates the diagnosis of male infertility. The aim of this Special Issue is to gather together in vitro evidence on SC physiology, causes of SC dysfunction, and to suggest a practical approach to be adopted in children.
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