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Update on Sjögren's Syndrome 2018
Ourania D Argyropoulou1, Athanasios G Tzioufas1
1Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Greece.
Mediterranean Journal of Rheumatology
|March 19, 2020
Summary
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease with unknown causes. This review explores recent findings on its pathogenesis, clinical signs, and potential new treatments for pSS.
Area of Science:
- Immunology
- Rheumatology
- Autoimmune Diseases
Background:
- Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disorder.
- It presents with diverse clinical manifestations, including exocrine dysfunction and extraglandular involvement.
- The exact etiology of pSS is unknown, but likely involves genetic and environmental factors.
Purpose of the Study:
- To review recent literature on the pathogenesis of pSS.
- To summarize the diverse clinical features of pSS.
- To discuss emerging therapeutic strategies for pSS.
Main Methods:
- Literature review of recent scientific publications.
- Synthesis of information on pSS pathogenesis.
- Compilation of data on clinical manifestations and therapeutic advancements.
Main Results:
- Pathogenesis of pSS remains incompletely understood.
- A wide spectrum of clinical symptoms characterizes pSS.
- Novel therapeutic targets and interventions are under investigation.
Conclusions:
- Further research is needed to elucidate the complex pathogenesis of pSS.
- Comprehensive management strategies are essential for addressing the multifaceted clinical picture of pSS.
- Advancements in understanding pSS offer hope for improved therapeutic outcomes.
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