Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

1.4K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.4K
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

265
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
265

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anakinra for recurrent pericarditis: a retrospective evaluation of long-term effectiveness, initiation timing and tapering.

Rheumatology international·2026
Same author

Disease-related and psychosocial factors associated with difficult-to-manage and treatment-refractory axial spondyloarthritis: insights from the Greek AxSpA Registry.

Rheumatology international·2026
Same author

Immunothrombosis promotes the interaction between neutrophils and synovial fibroblasts in rheumatoid arthritis.

Translational research : the journal of laboratory and clinical medicine·2026
Same author

Clonal Hematopoiesis of Indeterminate Potential (CHIP): A Model of Mutation-Driven Thromboinflammation.

Cancers·2026
Same author

Beyond Clinical Trials: Experience with Bimekizumab in 3 Challenging Cases of Psoriatic Arthritis.

Mediterranean journal of rheumatology·2026
Same author

HCV Reactivation Risk in Patients Undergoing Treatment for Inflammatory Arthritis and Connective Tissue Diseases.

Mediterranean journal of rheumatology·2026

Related Experiment Video

Updated: Dec 26, 2025

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

8.2K

Complex Regional Pain Syndrome: An update.

Christina Misidou1, Charalampos Papagoras1

  • 1First Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece.

Mediterranean Journal of Rheumatology
|March 19, 2020
PubMed
Summary

Complex regional pain syndrome (CRPS) is a painful extremity condition often affecting middle-aged women. Current diagnostic and treatment strategies for CRPS remain challenging due to its complex pathophysiology.

Keywords:
Complex regional pain syndromealgoneurodystrophycausalgianeuropathic painnociceptive painreflex sympathetic dystrophy

More Related Videos

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.4K
Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
09:16

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

Published on: February 16, 2017

17.4K

Related Experiment Videos

Last Updated: Dec 26, 2025

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
07:12

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Published on: January 21, 2020

8.2K
Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
03:26

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

Published on: March 8, 2024

3.4K
Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing
09:16

Dynamic Quantitative Sensory Testing to Characterize Central Pain Processing

Published on: February 16, 2017

17.4K

Area of Science:

  • Pain Medicine
  • Neurology
  • Rheumatology

Background:

  • Complex regional pain syndrome (CRPS) is a debilitating condition affecting extremities, often post-injury.
  • CRPS presents with sensory, motor, autonomic, and trophic disturbances, evolving through acute and chronic phases.
  • Prevalence varies, with a predilection for middle-aged women and upper limb involvement.

Purpose of the Study:

  • To provide a comprehensive overview of Complex Regional Pain Syndrome (CRPS).
  • To discuss the diagnostic challenges and current understanding of CRPS pathophysiology.
  • To review existing and potential treatment modalities for CRPS.

Main Methods:

  • Literature review of Complex Regional Pain Syndrome (CRPS) studies.
  • Analysis of clinical presentation, diagnostic criteria, and pathophysiological mechanisms.
  • Evaluation of current and experimental therapeutic interventions for CRPS.

Main Results:

  • No definitive diagnostic tests exist for CRPS; proposed criteria lack validation.
  • Pathophysiology likely involves neuroinflammation, autonomic dysfunction, psychological factors, and potential autoimmunity.
  • Effective treatments remain elusive, with bisphosphonates, glucocorticoids, and physical therapy showing some promise.

Conclusions:

  • CRPS diagnosis and management require further research and validated criteria.
  • Understanding the multifaceted pathophysiology is crucial for developing targeted therapies.
  • Multimodal treatment approaches, including pharmacological and rehabilitative strategies, are essential for CRPS patients.