Related Experiment Video
Updated: Dec 26, 2025
08:07
Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
Published on: September 6, 2017
10.5K
The novel HLA-B*07:387 allele, identified by next-generation sequencing in a Saudi individual
Dunia Jawdat1, Yasser Almutairi1, Qamariyyah Alnafie1
1Saudi Stem Cell Donor Registry, King Abdullah International Medical Research Center/College of Science and Health Professions, King Saud bin Abdulaziz University for Health Sciences/King Abdulaziz Medical City-Riyadh, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
HLA
|March 19, 2020
Abstract:
HLA-B*07:387 differs from HLA-B*07:05:01:01 by a single nucleotide substitution in codon 91 (Glycine to Tryptophan).
Related Concept Videos
01:11Genome-wide Association Studies-GWAS
15.2K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
15.2K
01:05Single Nucleotide Polymorphisms-SNPs
17.7K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
17.7K