Effects of san-huang-hsieh-hsin-tang on central monoaminergic and GABAergic systems in rats
Related Experiment Videos
1Department of Biochemistry, Chung Shan Medical and Dental College, Taichung, Taiwan.
The American Journal of Chinese Medicine
|January 1, 1988
Abstract:
In this paper, the effects of San-Huang-Hsieh-Hsin-Tang on central monoaminergic and GABAergic systems were studied in rats. It was found that San-Huang-Hsieh-Hsin-Tang significantly (1) prolonged the period from the onset of clonic to tonic convulsions induced by picrotoxin, (2) prolonged the sleep duration induced by hexobarbital, (3) inhibited central catecholaminergic activity, (4) promoted central GABAergic activity, and (5) decreased the turnovers of central norepinephrine and dopamine.