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The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
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Are Established Embedded Performance Validity Test Cut-Offs Generalizable to Patients With Multiple Sclerosis?
Christopher H Domen1, Michael R Greher1, Patrick W Hosokawa2
1Department of Neurosurgery, University of Colorado School of Medicine, Aurora, CO, USA.
Summary
Embedded performance validity tests (ePVTs) show promise for multiple sclerosis (MS) patients, with established cut-offs generally performing well. Further research is needed for MS patients with more advanced disease.
Area of Science:
- Neuropsychology
- Neurology
- Clinical Psychology
Background:
- Limited data exists on embedded performance validity tests (ePVTs) in multiple sclerosis (MS) populations.
- Assessing cognitive performance in MS requires reliable validity measures.
Purpose of the Study:
- To evaluate the performance of previously validated ePVTs in a sample of MS patients.
- To determine if ePVTs validated in other neurological conditions maintain similar performance in MS.
Main Methods:
- Retrospective analysis of ePVT performance in MS patients.
- Calculation of below-criterion responding prevalence at various cut-off scores.
- Inclusion of MS patients who passed a stand-alone performance validity test (PVT).
Main Results:
- Established PVT cut-offs demonstrated acceptable specificity in the MS sample.
- The cognitive burden in the study sample was less than in previous large-scale MS studies.
- Most validated cut-offs for ePVTs did not yield excessive false positives in this MS cohort.
Conclusions:
- Initial data suggest select ePVTs are viable for use in MS populations.
- Current findings support the use of previously validated cut-offs for ePVTs in relapsing-remitting MS.
- Further validation is recommended for MS patients with more advanced disease stages.
