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Updated: Dec 26, 2025

Author Spotlight: Integrating Alveolar-Capillary Reserve Measurements in Exercise Adaptation and Therapeutic Strategies
Published on: February 2, 2024
[Dyspnoea]
Agata M Makowska1,2, Harald T Jorstad3, Renée B A van den Brink3
1GGD Amsterdam, afd. Tuberculosebestrijding, Amsterdam.
Dyspnoea, or shortness of breath, is a common symptom in lung and heart conditions. This article answers key questions on its causes, diagnosis, and treatment, emphasizing a structured clinical approach.
Area of Science:
- Pulmonology
- Cardiology
- Internal Medicine
Background:
- Dyspnoea is a prevalent symptom in patients with pulmonary or cardiovascular diseases.
- It serves as a critical physiological signal, experienced during exertion and indicative of various underlying pathologies.
Purpose of the Study:
- To address 10 key questions regarding the causes of dyspnoea.
- To evaluate the efficacy of diagnostic and therapeutic interventions for dyspnoea.
- To propose a practical clinical strategy for assessing dyspnoea.
Main Methods:
- A comprehensive review and synthesis of current knowledge on dyspnoea.
- Development of a systematic approach for clinical assessment.
- Emphasis on differential diagnosis, mechanistic understanding, and timely intervention.
Main Results:
- Identification of common causes of dyspnoea in respiratory and cardiac patients.
- Evaluation of the effectiveness of diagnostic tools and therapeutic options.
- A proposed strategy focusing on severity assessment, differential diagnosis, and mechanism-based treatment.
Conclusions:
- Effective management of dyspnoea necessitates a thorough understanding of its causes and mechanisms.
- A structured, multidisciplinary approach is often required for optimal assessment and treatment.
- Timely intervention based on severity and underlying cause is crucial.
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