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Published on: March 27, 2018
Is myocardial revascularization really necessary in patients with ≥50% but <70% coronary stenosis undergoing valvular
Benedetto Del Forno1, Guido Ascione1, Elisabetta Lapenna1
1Department of Cardiac Surgery, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.
Insights
Omitting coronary artery bypass grafting in patients with moderate coronary artery stenosis undergoing valvular surgery is safe. This approach avoids unnecessary procedures and shows excellent long-term survival without cardiac events.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- Patients undergoing valvular surgery often present with moderate coronary artery stenosis.
- The necessity of coronary artery bypass grafting (CABG) in these patients is debated.
- Current guidelines may lead to overtreatment of coronary stenosis in this population.
Purpose of the Study:
- To evaluate the safety and efficacy of omitting coronary artery bypass grafting in patients with moderate coronary artery stenosis undergoing primary valvular surgery.
- To assess the immediate and mid-term clinical outcomes of this 'intentional omission strategy'.
Main Methods:
- A cohort of 77 patients with moderate coronary stenosis (50-70%) undergoing aortic or mitral valve surgery without prior symptoms of angina or ischemia were included.
- Coronary artery bypass grafting was intentionally omitted in all patients.
- Patients were followed for up to 6 years post-surgery.
Main Results:
- No in-hospital deaths occurred.
- Only one patient experienced postoperative acute myocardial infarction, treated successfully with percutaneous coronary intervention (PCI).
- The 6-year overall survival rate was 94.7%, with no cardiac deaths recorded. The cumulative incidence of PCI at 6 years was 8%.
Conclusions:
- Moderate coronary stenosis discovered incidentally during valvular surgery can often be safely managed without intervention.
- The 'intentional omission strategy' for CABG in selected patients undergoing valvular surgery is associated with favorable mid-term outcomes.
- This approach may be applicable to minimally invasive cardiac surgery, percutaneous procedures, and complex patient profiles.
Objectives:
The aim of this study is to evaluate the immediate and mid-term effects of omitting coronary artery bypass grafting in patients with moderate coronary artery stenosis who have a primary indication for valvular surgery.
Methods:
We included 77 consecutive patients admitted to our Institution for aortic or mitral valve surgery between June 2012 and June 2017 in whom a de novo diagnosis of ≥50%, but <70% coronary stenosis was made. In this cohort, the myocardial revascularization was omitted. All these patients were free from angina and ischaemia on echo and ECG.
Results:
There were no in-hospital deaths. In only 1 patient, acute myocardial infarction occurred postoperatively, which was immediately treated by percutaneous coronary intervention (PCI). The 6-year overall survival was 94.7 ± 2.59%. At 6 years, no cardiac deaths were recorded. At follow-up, 4 patients underwent elective PCI after a positive stress myocardial perfusion test. Only 1 patient underwent urgent PCI due to acute coronary syndrome. At 6 years, the cumulative incidence function of PCI, with death as competing risk, was 8 ± 3.9%.
Conclusions:
In our experience, moderate coronary stenosis, occasionally discovered at the time of valvular heart surgery, can be safely overlooked and do not need any further treatment at follow-up in the majority of cases. Our results open up the opportunity to apply this 'intentional omission strategy' in different situations, such as minimally invasive heart surgery, percutaneous procedures and complex patients.
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