Is myocardial revascularization really necessary in patients with ≥50% but <70% coronary stenosis undergoing valvular

Benedetto Del Forno1, Guido Ascione1, Elisabetta Lapenna1

  • 1Department of Cardiac Surgery, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.

Insights

Omitting coronary artery bypass grafting in patients with moderate coronary artery stenosis undergoing valvular surgery is safe. This approach avoids unnecessary procedures and shows excellent long-term survival without cardiac events.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Interventional Cardiology

Background:

  • Patients undergoing valvular surgery often present with moderate coronary artery stenosis.
  • The necessity of coronary artery bypass grafting (CABG) in these patients is debated.
  • Current guidelines may lead to overtreatment of coronary stenosis in this population.

Purpose of the Study:

  • To evaluate the safety and efficacy of omitting coronary artery bypass grafting in patients with moderate coronary artery stenosis undergoing primary valvular surgery.
  • To assess the immediate and mid-term clinical outcomes of this 'intentional omission strategy'.

Main Methods:

  • A cohort of 77 patients with moderate coronary stenosis (50-70%) undergoing aortic or mitral valve surgery without prior symptoms of angina or ischemia were included.
  • Coronary artery bypass grafting was intentionally omitted in all patients.
  • Patients were followed for up to 6 years post-surgery.

Main Results:

  • No in-hospital deaths occurred.
  • Only one patient experienced postoperative acute myocardial infarction, treated successfully with percutaneous coronary intervention (PCI).
  • The 6-year overall survival rate was 94.7%, with no cardiac deaths recorded. The cumulative incidence of PCI at 6 years was 8%.

Conclusions:

  • Moderate coronary stenosis discovered incidentally during valvular surgery can often be safely managed without intervention.
  • The 'intentional omission strategy' for CABG in selected patients undergoing valvular surgery is associated with favorable mid-term outcomes.
  • This approach may be applicable to minimally invasive cardiac surgery, percutaneous procedures, and complex patient profiles.
Abstract

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