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Updated: Dec 26, 2025
12:12
In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors
Published on: December 17, 2013
12.9K
Livestock pluripotency is finally captured in vitro
Micaela Navarro1, Delia A Soto1, Carlos A Pinzon2
1Department of Animal Science, University of California, 450 Bioletti Way, Davis, CA 95616, USA.
Reproduction, Fertility, and Development
|March 20, 2020
Summary
Stable livestock pluripotent stem cells (PSCs) are now available, opening new avenues for animal agriculture. These PSCs offer exciting applications in genome editing and cellular agriculture.
Area of Science:
- * Stem cell biology and developmental biology.
- * Animal science and agricultural technology.
Background:
- * Pluripotent stem cells (PSCs) are crucial for understanding mammalian development and regenerative medicine.
- * Advances in murine and human PSC research have enabled the generation of livestock PSCs.
Purpose of the Study:
- * To highlight the recent feasibility of generating stable livestock PSCs.
- * To explore novel applications of livestock PSCs in animal agriculture.
Main Methods:
- * Not explicitly detailed, but implies leveraging existing knowledge of pluripotency.
- * Focuses on the *potential* applications rather than specific experimental methods.
Main Results:
- * Stable livestock PSCs can now be generated.
- * Livestock PSCs are unlikely to be used for applications identical to human/murine PSCs.
Conclusions:
- * Livestock PSCs present significant opportunities for advancing animal agriculture.
- * Potential applications include complex genome editing, cellular agriculture, gamete generation, and in vitro breeding.
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