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Updated: Dec 26, 2025
Transient Transduction of the Strobilated Forms of Echinococcus granulosus
Published on: September 16, 2022
[Results of multimodal treatment of hepatic echinococcosis]
Stefan Heinrich1, Verena Tripke2, Tobias Huber2
1Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsmedizin Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland. stefan.heinrich@unimedizin-mainz.de.
Background:
Echinococcosis is a rare parasitosis in Germany for which the World Health Organization recommends stage-specific treatment strategies.
Objective:
The aim of this study was to analyze the treatment results of patients with hepatic echinococcosis at a German center of excellence for liver surgery.
Methods:
Patients who underwent surgery for hepatic echinococcosis between 2009 and 2018 at the University Hospital of Mainz (UMM) were included in this follow-up examination. The investigation included a magnetic resonance imaging (MRI) of the abdomen, documentation of the quality of life (QoL), serological and laboratory parameters. In addition, an online survey was performed among surgeons from Middle Rhein and gastroenterologists from Rhineland-Palatinate.
Results:
At the UMM 25 surgical interventions were performed for hepatic echinococcosis: 9 for cystic (CE) and 16 for alveolar echinococcosis (AE). The majority of the interventions were major liver resections with additional vascular and biliary procedures. The 90-day mortality was 0%, and 4 grade 3a and 1 grade 4b complications occurred. In contrast to AE 75% of the postoperative serological results of patients with CE remained positive for more than 1 year postoperatively. Most participants in the survey knew the imaging characteristics and treatment options of AE and CE; however, many participants were unaware of the cost of the treatment.
Conclusion:
From the perspective of surgeons, hepatic echinococcosis is a challenge, which however can be curatively treated with a low morbidity despite advanced disease in many patients. Due to the low incidence of the disease, the state of knowledge about AE and CE is limited among physicians.
