Silver Diammine Fluoride: Rejuvination of a 172-Year-Old (or Older?) Dental Caries Attenuation

In 2015, Elevate Oral Care (http://www.elevateoralcare.com) introduced a 38% silver diammine fluoride (SDF) solution to the dentistry marketplace in North America. The company named the product "Advantage Arrest™ Silver Diamine Fluoride 38%" (Figure 1). The chemistry and nomenclature for SDF (AgFH₆N₂) is described as such: "Silver diammine fluoride is a metal ammine complex of silver fluoride. The ammonia ligands are thus "ammine", but the term "amine" is sometimes used incorrectly for this chemical. In addition to that spelling difference, it is sometimes also called "ammoniacal silver fluoride", which is also sometimes improperly spelled as "ammonical silver fluoride."¹.