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Related Experiment Videos

[Thyroiditis and Turner's syndrome].

M Lecornu1, I Treussard, C Jezequel

  • 1Service de Pédiatrie A, Hôpital Sud, Rennes.

Archives Francaises De Pediatrie
|June 1, 1988
PubMed
Summary
This summary is machine-generated.

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Turner

Area of Science:

  • Endocrinology
  • Genetics
  • Autoimmune Diseases

Background:

  • Turner's syndrome (45,X) is a genetic condition affecting females.
  • Hashimoto's thyroiditis is an autoimmune disease causing hypothyroidism.
  • Co-occurrence of these conditions is noted in clinical practice.

Observation:

  • Two cases of Turner's syndrome with Hashimoto's thyroiditis are presented.
  • A high incidence of X chromosome abnormalities is observed in associated cases.
  • 17 out of 25 patients with Turner's syndrome and thyroiditis had structural X chromosome abnormalities.

Findings:

  • The karyotype 46 XX (iq), 45 X is frequently associated with this comorbidity.
  • Routine thyroid antibody screening is recommended for gonadal dysgenesis patients aged 10-20.

Related Experiment Videos

  • Early thyroid hormone replacement is crucial for Turner's syndrome with Hashimoto's thyroiditis.

    • Implications:

    • Early diagnosis and management can prevent long-term complications of hypothyroidism.
    • This highlights the importance of screening for autoimmune thyroid disease in Turner's syndrome.
    • Understanding the genetic link may inform future research and therapeutic strategies.