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Primary CNS lymphoma initially diagnosed as vasculitis
Lauren Feldman1, Yuebing Li1, Daniel Ontaneda1
1Neurological Institute, Cleveland Clinic, OH.
Purpose Of Review:
A vasculitic pattern of injury seen on brain biopsy can be attributed to a multitude of primary or secondary disorders, leading to diagnostic challenges for clinicians.
Recent Findings:
This report describes the clinical presentation and histopathologic findings in 2 patients who initially received a diagnosis of primary CNS vasculitis, but did not show long-term response to treatment. In both cases, a second biopsy was performed, and the final diagnosis was primary CNS lymphoma (PCNSL).
Summary:
Analyzing diagnostically challenging cases can increase recognition of PCNSL and improve outcomes in this rare condition.
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