Related Experiment Video
Updated: Dec 26, 2025

08:17
Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
19.9K
A Rare Cause of Optic Neuropathy
Isabel O Cruz1, Sara Alves Pereira2, Bruna Vieira3
1Internal Medicine, Hospital Pedro Hispano, Porto, PRT.
Cureus
|March 20, 2020
Summary
Lyme neuroborreliosis can cause vision loss and meningitis, even in treated patients. Early diagnosis and antibiotic treatment are crucial for preventing complications from this tick-borne illness.
Area of Science:
- Neurology
- Infectious Diseases
- Ophthalmology
Background:
- Lyme disease, caused by Borrelia burgdorferi, is a tick-borne illness affecting multiple organ systems.
- Neurological complications, including meningitis and optic neuropathy, can occur, particularly in untreated cases.
Observation:
- A 48-year-old male presented with progressive vision loss in his right eye over two months.
- Examination revealed a relative afferent pupillary defect, and visual evoked potential testing showed bilateral P100 latency delay, indicating optic neuropathy.
- Cerebrospinal fluid analysis confirmed lymphocytic meningitis.
Findings:
- The patient was diagnosed with Lyme neuroborreliosis, presenting with meningitis and optic neuritis.
- Treatment with antibiotics led to gradual improvement.
- Follow-up MRI showed residual inflammation and gliosis on the right optic nerve.
Implications:
- Lyme neuroborreliosis should be considered in patients from endemic areas with unexplained neurological and ophthalmological symptoms.
- Prompt diagnosis and treatment are essential to prevent severe complications and long-term sequelae of Lyme disease.
Related Concept Videos
Photoreceptors and Visual Pathways
8.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.5K
Glaucoma: Overview
1.1K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.1K
Anatomy of the Eyeball
9.2K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
9.2K
The Retinoblastoma Gene
4.6K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.6K
Open Angle Glaucoma: Treatment
891
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
891
Angle Closure Glaucoma: Treatment
1.0K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.0K

