Paroxysmal Sympathetic Hyperactivity in a Young Male with Glioblastoma Multiforme

Paroxysmal sympathetic hyperactivity (PSH) is a rare syndrome that is a recognized complication of severe brain injury. It is characterized by episodic hypertension, hyperthermia, tachycardia, tachypnea, diaphoresis, and specific posturing. It is prevalent in an intensive care unit (ICU) setting where high acuity illnesses can mask the symptoms of PSH. Herein, we report a case of PSH in a patient with a past medical history significant for glioblastoma multiforme (GBM) status post hemicraniectomy, radiation, and chemotherapy.