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Updated: Dec 26, 2025

Multifocal Electroretinograms

Multifocal Electroretinograms

Published on: December 4, 2011

Electroretinogram abnormalities in non-infectious uveitis often persist.

Anna H Brouwer^1,2, Gerard C de Wit², Ninette H Ten Dam¹

¹Department of Ophthalmology, University Medical Centre Utrecht, Utrecht, the Netherlands.

Acta Ophthalmologica

|March 20, 2020

Summary

This summary is machine-generated.

In non-infectious uveitis, electroretinogram (ERG) abnormalities often persist. While some ERG improvements correlate with reduced inflammation, worsening is linked to ongoing active uveitis.

Keywords:

ERG electrophysiology electroretinogram electroretinography uveitis

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Multifocal Electroretinograms

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Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

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Published on: July 1, 2016

Area of Science:

Ophthalmology
Neuroscience
Immunology

Background:

Prolonged cone b-wave implicit time is a hallmark electroretinogram (ERG) finding in uveitis.
The natural course and associated clinical factors of this ERG abnormality over time are not fully understood.

Purpose of the Study:

To investigate the temporal changes in cone b-wave implicit time in non-infectious uveitis.
To identify clinical factors associated with improvement or deterioration of ERG abnormalities.

Main Methods:

Prospective cohort study including patients with non-infectious uveitis.
Electroretinogram (ERG) measurements were taken within the first year of uveitis onset and at a one-year follow-up.
Changes in cone b-wave implicit time were analyzed against clinical parameters.

Main Results:

Of 98 eyes, 40 had prolonged cone b-wave implicit time; 10 improved, often with resolved anterior chamber inflammation in panuveitis.
Five eyes with normal initial ERGs showed deterioration, associated with active uveitis at follow-up.
Most ERG abnormalities remained stable, even with quiescent inflammation.

Conclusions:

Electroretinogram (ERG) abnormalities in non-infectious uveitis are largely irreversible, persisting even when inflammation subsides.
Improvement in ERG findings can occur, particularly with reduced anterior chamber inflammation in panuveitis.
Worsening of ERG parameters is associated with persistent active uveitis.