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Updated: Dec 25, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Brugada Syndrome Caused by Sodium Channel Dysfunction Associated with a SCN1B Variant A197V

Linlin Wang1, Zhonglin Han2, Jian Dai1

  • 1Department of Cardiology, Nanjing Brain Hospital, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, People's Republic of China.

Archives of Medical Research
|March 21, 2020
PubMed
Abstract

Keywords:
Brugada syndromeGene mutationSCN1BSCN5ASodium channel

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