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Related Concept Videos

Redox Reactions01:27

Redox Reactions

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Redox reactions are vital biochemical processes that underpin energy metabolism in cells. These reactions involve the transfer of electrons between molecules, occurring in tandem as oxidation and reduction. Oxidation refers to the loss of electrons, while reduction denotes their gain. This coupling ensures the seamless flow of electrons through metabolic pathways. For example, in bacterial metabolism, glucose undergoes oxidation to carbon dioxide, while oxygen is simultaneously reduced to...
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Redox Reactions01:24

Redox Reactions

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Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
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Redox Equilibria: Overview01:23

Redox Equilibria: Overview

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A reduction-oxidation reaction is commonly called a redox reaction. In a redox reaction, electrons are transferred from one species to another rather than being shared between or among atoms. The reducing agent or reductant is the species that loses electrons and gets oxidized in the process. The species that gains electrons and gets reduced in the process is the oxidizing agent or oxidant. Redox reactions are represented as two separate equations called half-reactions, where one equation...
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Oxidation and Reduction of Organic Molecules01:19

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Energy production within a cell involves many coordinated chemical pathways. Most of these pathways are combinations of oxidation and reduction reactions, which occur at the same time. An oxidation reaction strips an electron from an atom in a compound, and the addition of this electron to another compound is a reduction reaction. Because oxidation and reduction usually occur together, these pairs of reactions are called redox reactions.
The removal of an electron from a molecule, results in a...
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Balancing Redox Equations02:58

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Electrochemistry is the science involved in the interconversion of electrical and chemical reactions. Such reactions are called reduction-oxidation, or redox reactions. These important reactions are defined by changes in oxidation states for one or more reactant elements and include a subset of reactions involving the transfer of electrons between reactant species. Electrochemistry as a field has evolved to yield sufficient insights on the fundamental principles of redox chemistry and multiple...
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Oxidation-Reduction Reactions03:11

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Oxidation–Reduction Reactions
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Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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Redox basis of exercise physiology.

N V Margaritelis1, V Paschalis2, A A Theodorou3

  • 1Department of Physical Education and Sport Science at Serres, Aristotle University of Thessaloniki, Thessaloniki, Greece; Dialysis Unit, 424 General Military Hospital of Thessaloniki, Thessaloniki, Greece.

Redox Biology
|March 21, 2020
PubMed
Summary
This summary is machine-generated.

Redox reactions, crucial for human biology, also drive exercise responses and adaptations. This review highlights how redox signaling underpins exercise physiology, from acute responses to chronic adaptations.

Keywords:
AdaptationsAntioxidantsExerciseRedox biologyResponsesSignaling

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Area of Science:

  • Exercise Physiology
  • Biochemistry
  • Cellular Biology

Background:

  • Redox reactions are fundamental to human biological processes.
  • Exercise physiology involves complex physiological responses and adaptations.
  • The role of redox reactions in exercise is increasingly recognized.

Purpose of the Study:

  • To demonstrate that redox reactions form the basis of exercise physiology.
  • To outline redox signaling pathways involved in exercise.
  • To emphasize the central role of redox regulation in exercise adaptations.

Main Methods:

  • Review of existing literature on redox reactions and exercise physiology.
  • Analysis of redox signaling pathways regulating acute exercise responses.
  • Examination of redox signaling pathways regulating chronic exercise adaptations.

Main Results:

  • Redox signaling pathways regulate key acute exercise responses: muscle contractile function, glucose uptake, blood flow, and bioenergetics.
  • Redox signaling pathways are involved in key chronic exercise adaptations: mitochondrial biogenesis, muscle hypertrophy, angiogenesis, and redox homeostasis.
  • The identified pathways support the central role of redox reactions in exercise.

Conclusions:

  • Redox reactions are integral to exercise physiology.
  • Redox signaling pathways mediate critical exercise-induced responses and adaptations.
  • Redox regulation should be considered a central tenet of exercise physiology.