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Updated: Dec 25, 2025

Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer
Published on: April 21, 2022
Mucins and their receptors in chronic lung disease
Emma Denneny1, Jagdeep Sahota1, Richard Beatson2
1Leukocyte Trafficking Laboratory Centre for Inflammation and Tissue Repair UCL Respiratory Rayne Institute University College London London UK.
Abstract:
There is growing recognition that mucus and mucin biology have a considerable impact on respiratory health, and subsequent global morbidity and mortality. Mucins play a critical role in chronic lung disease, not only by providing a physical barrier and clearing pathogens, but also in immune homeostasis. The aim of this review is to familiarise the reader with the role of mucins in both lung health and disease, with particular focus on function in immunity, infection and inflammation. We will also discuss their receptors, termed glycan-binding proteins, and how they provide an attractive prospect for therapeutic intervention.
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