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Updated: Apr 3, 2026

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
Published on: January 8, 2013
Computer simulations of cardiac action potentials in two dimensions
1Physics Department, Vanderbilt University, Nashville, TN 37235.
Abstract:
A novel method of calculation is presented which allows computer simulations of action potentials for a two-dimensional, planar reconstruction of the depolarization phase of a cardiac action potential to be followed through nonuniform tissue. The calculation is explicit in type and assumes an infinite, grounded extracellular region. A 70 by 70 point region is calculated swiftly on a PC/AT. Results show elliptical isochrones when slow and fast directions have different resistivities. The time derivative of Vm is, however, similar in both directions. Insertion of a test region of tissue with high resistance results in wave-like propagation of the A.P. around the 'bad' region.
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