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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.1K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.1K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.3K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.3K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.0K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.0K
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

3.6K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.6K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

1.6K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
1.6K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

3.9K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
3.9K

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Related Experiment Video

Updated: Dec 25, 2025

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
07:28

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

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Feasibility Study of Asthma Cream.

Andrew Kuang1

  • 1Canyon Crest Academy, San Diego, California. andrewkuang11@gmail.com.

International Journal of Pharmaceutical Compounding
|March 21, 2020
PubMed
Summary

Topical asthma creams offer a new treatment option for patients unable to use inhalers. This study shows a cream can deliver asthma medication effectively, matching oral drug bioavailability.

Area of Science:

  • Pharmacology
  • Dermatology
  • Respiratory Medicine

Background:

  • Asthma affects millions, incurring significant healthcare costs.
  • Conventional asthma treatments (inhalers, oral medications) are inaccessible for some patients due to swallowing or inhalation difficulties.

Purpose of the Study:

  • To investigate topical creams as an alternative delivery method for asthma medication.
  • To assess the feasibility of using a cream formulation for asthma treatment.

Main Methods:

  • A cream was formulated with an orally administered asthma drug and a suitable base.
  • The cream's efficacy was tested in mice, with topical application to the back.
  • Drug bioavailability was analyzed in blood samples using mass spectrometry at various time points.

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Related Experiment Videos

Last Updated: Dec 25, 2025

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Main Results:

  • The topical cream successfully delivered the asthma drug.
  • The drug bioavailability achieved via the cream matched that of oral montelukast sodium.
  • The cream formulation demonstrated potential for effective transdermal drug delivery.

Conclusions:

  • Topical asthma creams represent a viable alternative delivery system for asthma patients.
  • This method can benefit individuals with conditions precluding traditional asthma medication use.
  • Topical creams may improve treatment adherence and outcomes for a wider asthma patient population.