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Updated: Dec 25, 2025

Manufacture and Drug Delivery Applications of Silk Nanoparticles
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Emerging methods in therapeutics using multifunctional nanoparticles.

Nahal Habibi1, Daniel F Quevedo2, Jason V Gregory1

  • 1Biointerfaces Institute, Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
|March 21, 2020
PubMed
Summary
This summary is machine-generated.

Multifunctional nanoparticles offer new solutions for drug delivery challenges like poor circulation and targeting. These advanced nanomedicine platforms are being explored for cancer therapy, medical imaging, and immunotherapy.

Keywords:
blood-brain barriercancer therapycellular hitchhikingclinical trialsdrug deliverymultifunctional nanoparticlesnanomedicineprotein nanoparticles

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Area of Science:

  • Nanomedicine
  • Nanotechnology in Biology
  • Biomaterials

Background:

  • Clinical translation of nanoparticle drug delivery faces challenges such as limited circulation and targeting.
  • Novel strategies are emerging to overcome these obstacles in nanomedicine.

Purpose of the Study:

  • To review the current landscape of multifunctional nanoparticle drug delivery systems.
  • To highlight opportunities, challenges, and future directions in the field.

Main Methods:

  • Review of current research on multifunctional nanoparticles.
  • Focus on protein-based nanoparticles and cell-mediated delivery systems.

Main Results:

  • Multifunctional nanoparticles show promise in overcoming traditional delivery limitations.
  • These systems are being investigated for diverse applications including cancer therapy, imaging, and immunotherapy.

Conclusions:

  • Next-generation multifunctional nanoparticle drug delivery platforms hold significant potential.
  • Continued research is crucial for advancing nanomedicine applications.