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Updated: Dec 25, 2025

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases
Published on: December 6, 2016
Intracranial vessel wall imaging: applications, interpretation, and pitfalls.
D J Leao1, A Agarwal2, S Mohan3
1Federal University of Uberlandia, Av. Amazonas, 1996 - Jardim Umuarama, Uberlandia, MG, 38405-302, Brazil.
Vessel wall imaging (VWI) offers a non-invasive view of the vascular wall, moving beyond lumen assessment. This review details VWI applications, interpretation, and findings for various cerebrovascular conditions.
Area of Science:
- Radiology
- Neurology
- Vascular Imaging
Background:
- Conventional vascular imaging focuses on the vessel lumen.
- Vessel wall imaging (VWI) shifts analysis to the vessel wall itself.
- Technical advancements are increasing VWI's clinical utility.
Purpose of the Study:
- To review the principles and applications of VWI.
- To discuss common imaging findings and interpretation strategies.
- To highlight potential pitfalls in VWI analysis.
Main Methods:
- Review of current literature on VWI.
- Discussion of VWI principles and technical considerations.
- Synthesis of imaging findings for various cerebrovascular diseases.
Main Results:
- VWI is valuable for diagnosing intracranial atherosclerosis, dissection, vasculitides (PACNS, neurosarcoidosis), and vasculopathies (RCVS, moyamoya disease, radiation-induced arteriopathy).
- VWI aids in evaluating aneurysms and post-thrombectomy changes.
- Understanding common findings and potential pitfalls is crucial for accurate interpretation.
Conclusions:
- VWI is an evolving, non-invasive tool for comprehensive cerebrovascular assessment.
- The review provides a guide to VWI interpretation for diverse clinical scenarios.
- Awareness of VWI limitations and pitfalls enhances diagnostic accuracy.
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