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Contrast-Enhanced Urodynamic Vector Projectile Imaging (CE-UroVPI) for Urethral Voiding Visualization: Principles and
Takuro Ishii1, Hassan Nahas1, Billy Y S Yiu1
1Schlegel Research Institute for Aging & Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, Canada.
Urology
|March 22, 2020
Summary
A new imaging method, contrast-enhanced urodynamic vector projectile imaging (CE-UroVPI), visualizes urinary flow and urethral changes during voiding. It revealed unique flow patterns in obstructed bladders, aiding lower urinary tract symptom research.
Area of Science:
- Medical Imaging
- Fluid Dynamics
- Urology
Background:
- Understanding the initiation phase of voiding is crucial for diagnosing lower urinary tract symptoms.
- Current imaging techniques lack the temporal resolution to capture rapid changes during early voiding.
Purpose of the Study:
- To develop a novel imaging framework for time-resolved visualization of urinary flow and urethral deformation.
- To investigate the spatiotemporal urodynamics during the initiation of voiding.
Main Methods:
- Contrast-enhanced urodynamic vector projectile imaging (CE-UroVPI) was developed using high-frame rate ultrasound and microbubble contrast agents.
- Performance was assessed using deformable urethra phantoms simulating healthy and benign prostatic hyperplasia (BPH)-obstructed conditions.
- Flow vector mapping was employed to analyze spatiotemporal urodynamics.
Main Results:
- CE-UroVPI achieved 1,250 fps (0.8 ms resolution), capturing transient voiding events.
- BPH-obstructed urethra showed anomalous flow: a speed surge upstream and complex jets/vortices downstream.
- Healthy urethra exhibited normal flow dynamics without these anomalies.
Conclusions:
- CE-UroVPI is the first framework to visualize complex urodynamics throughout voiding, including initiation.
- This tool offers potential for new insights into the link between urethral factors and lower urinary tract symptoms.
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