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Updated: Dec 25, 2025

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response
Published on: January 12, 2017
Cooperation and life history evolution help obligate parasites to circumvent host genetic deficiencies
Zachary M Bailey1, Carolin Wendling1
1Department of Environmental Systems Science, ETH Zürich, Zürich, 8092, Switzerland.
Abstract:
How do obligate parasites cope with hosts that lack genetic elements required for parasite replication? Gupta et. al. (2020) illustrate an experimental evolution system where lambda bacteriophages circumvent a defective gene network in their E. coli host (which initially made it impossible for them to replicate) through both intracellular cooperation and evolutionary changes in phage life-history traits.
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