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Updated: Dec 25, 2025

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Comparison of response adaptive randomization features in multiarm clinical trials with control

Kert Viele1,2, Benjamin R Saville1,3, Anna McGlothlin1

  • 1Berry Consultants, Austin, Texas, USA.

Pharmaceutical Statistics
|March 22, 2020
PubMed
Summary

Response adaptive randomization (RAR) optimizes clinical trials by identifying the best treatment arm. Earlier RAR activation, frequent analyses, and aggressive arm dropping benefit both internal and external patient populations.

Keywords:
multiple arm clinical trialresponse adaptive randomization

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